The McLaren MP4/6 is a Formula One racecar that was designed by Neil Oatley for the 1991 F1 season. It was the first McLaren to be powered by a Honda V12 engine. The car was tested by Gerhard Berger in the off-season, but he was unimpressed with the new engine, feeling it was underpowered for what it was, especially compared to Honda's V10 engine in the previous year's car. When Ayrton Senna returned for pre-season testing, he knuckled down to try to solve the engine's problems. McLaren's domination in the early part of the year was mainly due to the lack of reliability of the Williams FW14.

MP4/6 1991 yılı boyunca manuel H model vites kutusuyla yarıştı. Sezon boyunca yarı otomatik bir şanzıman test edildi, ancak hiçbir zaman bir yarışta kullanılacak kadar iyi olarak görülmedi. Ferrari ve Williams 1991 yılında yarı otomatik vites kutusu kullanan tek takımlardı. Bu da MP4/6'yı manuel şanzıman ya da V12 motor kullanarak sürücüler ya da yapımcılar arasında Dünya Şampiyonluğu kazanan son Formula 1 aracı yapmaktadır.

Senna won the first four races of the season, in the United States, an emotional victory in Brazil, San Marino and Monaco before...